SCHEMBL40532

SCHEMBL40532

N#Cc1cccc(C(=O)Cl)c1

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 2/20 0.61
P4HB P07237 4/20 0.49
FBP1 P09467 1/20 0.49
GRM5 P41594 3/20 0.48
ALDH1A1 P00352 2/20 0.46
TSHR P16473 1/20 0.46
CLK1 P49759 1/20 0.46
DYRK1A Q13627 1/20 0.46
DYRK1B Q9Y463 1/20 0.46
ENPP2 Q13822 1/20 0.46
MEN1 O00255 1/20 0.45
MAPT P10636 1/20 0.45
KMT2A Q03164 1/20 0.45
VNN1 O95497 2/20 0.44
IRAK4 Q9NWZ3 1/20 0.44
KAT6A Q92794 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31575813 1.00 GSK3B (0.61) GSK3BP4HBFBP1GRM5ALDH1A1
Fluorobenzene SCHEMBL28928512 0.88 GSK3B (0.50) GSK3BP4HBFBP1VNN1KAT6A
SCHEMBL2104597 0.84 BRAF (0.56) GRM5ALDH1A1MEN1MAPTKMT2A
SCHEMBL2164429 0.82 GSK3B (0.62) GSK3BP4HBGRM5ALDH1A1CLK1
SCHEMBL103415 0.82 ALDH1A1 (0.47) GSK3BP4HBFBP1GRM5ALDH1A1
SCHEMBL60691 0.82 GSK3B (0.62) GSK3BGRM5
SCHEMBL29441888 0.82 GSK3B (0.62) GSK3BGRM5
Benzoyl Chloride SCHEMBL8174168 0.81 VNN1 (0.46) GSK3BGRM5KMT2AVNN1IRAK4
SCHEMBL23079142 0.80 GSK3B (0.61) GSK3BP4HBGRM5ALDH1A1CLK1
SCHEMBL14508038 0.80 GSK3B (0.51) GSK3BP4HBFBP1GRM5ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1520 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114773606-B Preparation method of selenium-containing hyperbranched polymer with ester bond as core 湖北宜化新材料科技有限公司 2023-03-31 CN claimed
CN-114853627-A Substituted docosahexaenoic acid diethyl ester derivative as well as preparation method and application thereof 自然资源部第三海洋研究所 2022-08-05 CN claimed
CN-114773606-A Preparation method of selenium-containing hyperbranched polymer with ester bond as core 湖北宜化新材料科技有限公司 2022-07-22 CN claimed
EP-1721891-A1 Method for producing cyanophenyl derivatives Showa Denko Kabushiki Kaisha (JP) 2006-11-15 EP claimed
US-6262292-B1 FORMING CYANAOBENZALDEHYDE BY OXIDATION OF CYANOBENZYLAMINE SHOWA DENKO K.K. (JP) 2001-07-17 US claimed
EP-1083165-A1 PROCESSES FOR PRODUCING CYANOPHENYL DERIVATIVES Showa Denko Kabushiki Kaisha (JP) 2001-03-14 EP claimed
WO-1993014055-A1 PREPARATION OF 2,5-DICHLOROBENZOPHENONES MAXDEM INCORPORATED (US) 1993-07-22 WO claimed
US-5210313-A Friedel crafts aryloylation of 1,4-dichlorobenzene and Lewis acids MAXDEM INCORPORATED (US) 1993-05-11 US claimed
CN-122071464-A Heterocyclic compound, pharmaceutical composition thereof and application thereof 上海璎黎药业有限公司 2026-05-22 CN disclosed
CN-122010947-A Antagonists of adenosine A2a receptors 阿道尔克斯治疗有限公司 2026-05-12 CN disclosed
US-12617796-B2 Antagonists of the adenosine A2a receptor JANSSEN PHARMACEUTICA NV (BE) 2026-05-05 US disclosed
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof GUANGZHOU VINNOCENT PHARMACEUTICAL LTD (CN) 2026-04-02 US disclosed
US-20260022098-A1 BULLEYACONITINE A DERIVATIVE WITH ANALGESIC ACTIVITY, AND PREPARATION METHOD AND APPLICATION THEREOF UNIV SOUTHWEST JIAOTONG (CN) 2026-01-22 US disclosed
US-12522614-B2 Topical phosphoinositide 3-kinase inhibitors VENTHERA, INC. (US) 2026-01-13 US disclosed
US-4192890-A Novel benzoylphenylacetic acid esters ROUSSEL UCLAF (FR) 1980-03-11 US disclosed
US-4085090-A Aromatic polymers containing a nitrogen-containing ring group, and process for preparation thereof TEIJIN LIMITED (JA) 1978-04-18 US disclosed
US-4069224-A N-(PYRIDYLALKYL)BENZAMIDES, IMPROVE PRODUCTION OF PROSTAGLANDINS IN MAMMALS THE UPJOHN COMPANY (US) 1978-01-17 US disclosed
US-4024153-A ULTRAVIOLET STABILIZERS EASTMAN KODAK COMPANY (US) 1977-05-17 US disclosed
US-3954706-A Polychromophoric benzotriazole ultraviolet stabilizers for organic compositions EASTMAN KODAK COMPANY (US) 1976-05-04 US disclosed
US-3939162-A Anthrapyrimidine dyes BASF AKTIENGESELLSCHAFT (DT) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260022098-A1 BULLEYACONITINE A DERIVATIVE WITH ANALGESIC ACTIVITY, AND PREPARATION METHOD AND APPLICATION THEREOF OPRD1, OPRM1, OPRK1 GSK3B 1268/4885P4HB 1108/4885FBP1 3429/4885
US-12617796-B2 Antagonists of the adenosine A2a receptor ADORA2A, ADORA2B, ADORA3 GSK3B 732/4885P4HB 4360/4885FBP1 765/4885
US-20260092074-A1 Annelated Pyridines as Steroidogenesis Inhibitors, Preparation Method and Use Thereof STS, NR5A1, CYP21A2 GSK3B 3896/4885P4HB 757/4885FBP1 227/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.