Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 3/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | BACE1 | P56817 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28929001 | 0.88 | MEN1 (0.38) | CES1MEN1KMT2APABPC1RXFP1 | |
| SCHEMBL28928994 | 0.84 | NTRK1 (0.46) | MEN1KMT2AMAPTMAPK1HDAC4 | |
| SCHEMBL28929027 | 0.82 | ALDH1A1 (0.49) | MEN1KMT2ARXFP1ALDH1A1MAPT | |
| SCHEMBL28929057 | 0.80 | ALOX5 (0.49) | MEN1KMT2AALDH1A1MAPTADORA3 | |
| SCHEMBL28929049 | 0.79 | L3MBTL1 (0.44) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL30165992 | 0.79 | L3MBTL1 (0.44) | MEN1KMT2AALDH1A1MAPTMAPK1 | |
| SCHEMBL28928975 | 0.78 | CDC25A (0.46) | CES1MEN1KMT2APABPC1ALDH1A1 | |
| SCHEMBL28929012 | 0.78 | NPSR1 (0.47) | CES1MEN1KMT2APABPC1RXFP1 | |
| SCHEMBL10015442 | 0.77 | CES1 (0.57) | CES1MEN1KMT2APABPC1ALDH1A1 | |
| SCHEMBL2842601 | 0.77 | KMT2A (0.61) | CES1MEN1KMT2APABPC1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583876-B | Phenyl naphthacene ketone compound and preparation method and application thereof | 深圳技术大学 | 2023-12-19 | — | — | CN | disclosed |
| CN-115583876-A | Phenyl-naphthalenepophenone compounds, preparation method and application thereof | 深圳技术大学 | 2023-01-10 | — | — | CN | disclosed |