Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.42 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | VIP | P01282 | 1/20 | 0.41 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.40 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928838 | 0.90 | PKM (0.56) | PKMDAOCREBBPALDH1A1KMT2A | |
| SCHEMBL28928854 | 0.86 | PKM (0.52) | PKMDAOCREBBPNPC1ALDH1A1 | |
| SCHEMBL28929420 | 0.85 | DAO (0.48) | PKMDAOCREBBPNPC1ALDH1A1 | |
| SCHEMBL28928873 | 0.83 | DAO (0.49) | PKMDAOCREBBPALDH1A1KMT2A | |
| SCHEMBL28928863 | 0.83 | DAO (0.49) | PKMDAOCREBBPALDH1A1KMT2A | |
| SCHEMBL28962239 | 0.79 | DAO (0.46) | PKMDAOCREBBPALDH1A1KMT2A | |
| SCHEMBL6202193 | 0.78 | KMT2A (0.55) | ALDH1A1KMT2AMAPTMEN1GSK3B | |
| SCHEMBL28928861 | 0.76 | PKM (0.50) | PKMDAOCREBBPNPC1VIP | |
| SCHEMBL28928830 | 0.76 | MEN1 (0.64) | NPC1ALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL6200322 | 0.76 | MEN1 (0.62) | NPC1ALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |