Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28962239 | 0.88 | DAO (0.46) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28928838 | 0.87 | PKM (0.56) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28928874 | 0.86 | DAO (0.46) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28928854 | 0.83 | PKM (0.52) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28929419 | 0.83 | PKM (0.52) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28928863 | 0.82 | DAO (0.49) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28928839 | 0.79 | DAO (0.44) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28962238 | 0.78 | PKM (0.47) | DAOPKMCREBBPALDH1A1KMT2A | |
| SCHEMBL28929418 | 0.78 | NPC1 (0.59) | ALDH1A1KMT2AHPGDCYP2C9SMN1; SMN2 | |
| SCHEMBL1193504 | 0.78 | NPC1 (0.65) | PKMALDH1A1KMT2AHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |