Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | VIP | P01282 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | KCNA6 | P17658 | 1/20 | 0.38 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.38 |
| ▸ | KCNA4 | P22459 | 1/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28928838 | 0.87 | PKM (0.56) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28928865 | 0.86 | DAO (0.46) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28929419 | 0.83 | PKM (0.52) | DAOPKMCREBBPHTTSMN1; SMN2 | |
| SCHEMBL28928854 | 0.83 | PKM (0.52) | DAOPKMCREBBPHRH3HTT | |
| SCHEMBL28928873 | 0.82 | DAO (0.49) | DAOPKMCREBBPHTTSMN1; SMN2 | |
| SCHEMBL28962239 | 0.79 | DAO (0.46) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28929186 | 0.78 | PKM (0.47) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL28928841 | 0.78 | CYP1A2 (0.48) | HDAC1HDAC6SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28928839 | 0.75 | DAO (0.44) | DAOPKMCREBBPHRH3ADRA2A | |
| SCHEMBL23014396 | 0.73 | ALDH1A1 (0.54) | HDAC1HDAC6HTTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115583942-A | 2-substituted 5-phenyl-oxazole derivative, preparation method thereof and application thereof as MNK (MNK) inhibitor | 中国海洋大学 | 2023-01-10 | — | — | CN | disclosed |