Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CDC7 | O00311 | 3/20 | 0.49 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10997300 | 0.82 | LMNA (0.60) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL299586 | 0.81 | CDC7 (0.61) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL299345 | 0.80 | MAPT (0.56) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL299133 | 0.79 | LMNA (0.63) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL13117989 | 0.77 | CDC7 (0.51) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL1982226 | 0.77 | CDC7 (0.48) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL2185567 | 0.77 | CDC7 (0.48) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL4449310 | 0.77 | XDH (0.55) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL299564 | 0.77 | CDC7 (0.53) | LMNAALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL6336462 | 0.77 | CDC7 (0.61) | ALDH1A1KDM4EMEN1KMT2ACDC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |