Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | CDC7 | O00311 | 5/20 | 0.62 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | TRPM8 | Q7Z2W7 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3370278 | 0.84 | TRPM8 (0.58) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL10997300 | 0.84 | LMNA (0.60) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL4011362 | 0.84 | HTR2C (0.65) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL5640705 | 0.84 | CDC7 (0.56) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3367686 | 0.82 | CDC7 (0.55) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL1316281 | 0.82 | CDC7 (0.77) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL3371496 | 0.81 | SMN1; SMN2 (0.67) | KDM4EALDH1A1TRPM8MAPTHPGD | |
| SCHEMBL288994 | 0.81 | KDM4E (0.80) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL28485399 | 0.81 | HTR2B (0.53) | LMNACDC7DBF4KDM4EALDH1A1 | |
| SCHEMBL12034449 | 0.81 | CDC7 (0.69) | LMNACDC7DBF4KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | claimed |
| EP-2427447-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | Pike Pharma GmbH (CH) | 2012-03-14 | — | — | EP | disclosed |
| WO-2010128163-A2 | SMALL MOLECULE INHIBITORS OF INFLUENZA A AND B VIRUS AND RESPIRATORY SYNCYTIAL VIRUS REPLICATION | PIKE PHARMA GMBH (CH) | 2010-11-11 | — | — | WO | disclosed |
| WO-2010018458-A2 | PHENOL DERIVATIVES AND METHODS OF USE THEREOF | CRYSTALGENOMICS, INC. (KR) | 2010-02-18 | — | — | WO | disclosed |