Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.52 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 2/20 | 0.45 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | BACE1 | P56817 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4214296 | 0.86 | CHKA (0.50) | DRD4EPHX2ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL2734359 | 0.86 | HDAC1 (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC1 | |
| SCHEMBL2797701 | 0.84 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC1 | |
| SCHEMBL6418433 | 0.84 | DRD4 (0.56) | DRD4ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5070257 | 0.83 | HDAC1 (0.64) | EPHX2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL21088372 | 0.82 | HDAC1 (0.67) | EPHX2ALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL2651787 | 0.82 | HDAC1 (0.51) | ALDH1A1SMN1; SMN2HDAC1HPGDLMNA | |
| SCHEMBL377906 | 0.82 | DRD4 (0.64) | DRD4TEAD1MEN1KMT2ACXCR4 | |
| SCHEMBL8265691 | 0.81 | GPR119 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AHDAC1 | |
| SCHEMBL4771649 | 0.81 | RAB9A (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2ARAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2164829-A1 | A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF | Ildong Pharmaceutical Co., Ltd. (KR) | 2010-03-24 | — | — | EP | disclosed |
| WO-2008150089-A1 | A NEW PEPTIDE DEFORMYLASE INHIBITOR COMPOUND AND MANUFACTURING PROCESS THEREOF | ILDONG PHARMACEUTICAL CO., LTD. (KR) | 2008-12-11 | — | — | WO | disclosed |