Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10262984 | 0.83 | SLC6A3 (0.56) | MAPTPKMKMT2AMEN1TSHR | |
| SCHEMBL5805888 | 0.82 | MAPT (0.54) | MAPTPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL7888936 | 0.81 | MAPT (0.53) | MAPTPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL28932953 | 0.81 | MAPT (0.53) | MAPTPKMALDH1A1KMT2AMEN1 | |
| SCHEMBL23923919 | 0.79 | CYP1A2 (0.61) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL23923920 | 0.79 | CYP1A2 (0.61) | MAPTALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3449300 | 0.79 | RORC (0.55) | MAPTPKMALDH1A1CHRM2CHRM4 | |
| SCHEMBL5839366 | 0.79 | RORC (0.55) | MAPTPKMALDH1A1CHRM2CHRM4 | |
| SCHEMBL7887604 | 0.79 | RORC (0.55) | MAPTPKMALDH1A1CHRM2CHRM4 | |
| SCHEMBL14270533 | 0.78 | MAPT (0.62) | MAPTPKMALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427394-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2022-12-02 | — | — | CN | disclosed |