Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.46 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.46 |
| ▸ | CHRM5 | P08912 | 4/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.46 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.45 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7888936 | 1.00 | MAPT (0.53) | MAPTPKMTSHRPDE4APDE4B | |
| SCHEMBL5805888 | 0.90 | MAPT (0.54) | MAPTPKMTSHRPDE4APDE4B | |
| SCHEMBL6595892 | 0.87 | PDE4B (0.47) | MAPTPKMPDE4APDE4BPDE4C | |
| SCHEMBL13104885 | 0.86 | MAPT (0.53) | MAPTPKMTSHRPDE4APDE4B | |
| SCHEMBL5821047 | 0.84 | TACR1 (0.56) | MAPTPKMPDE4APDE4BPDE4C | |
| SCHEMBL10262984 | 0.83 | SLC6A3 (0.56) | MAPTPKMTSHRSLC6A3SLC18A2 | |
| SCHEMBL6592795 | 0.83 | ALDH1A1 (0.49) | MAPTPKMPDE4APDE4BPDE4C | |
| SCHEMBL28932947 | 0.81 | MAPT (0.53) | MAPTPKMTSHRCHRM2CHRM4 | |
| SCHEMBL23924117 | 0.81 | TLR2 (0.46) | SMN1; SMN2MEN1KMT2A | |
| SCHEMBL7885188 | 0.81 | TLR2 (0.46) | SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115427394-A | Heterocyclic compounds for modulating NR2F6 | TES制药有限责任公司 | 2022-12-02 | — | — | CN | disclosed |