Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 5/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.37 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.37 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 4/20 | 0.34 |
| ▸ | ESR1 | P03372 | 5/20 | 0.33 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 1/20 | 0.33 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.33 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.33 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.33 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20582043 | 0.84 | HTT (0.43) | TSHRSPHK1 | |
| SCHEMBL3634744 | 0.83 | TSHR (0.32) | ALDH1A1TSHRCA1CA2SPHK1 | |
| SCHEMBL7121852 | 0.78 | ALDH1A1 (0.52) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL22117615 | 0.77 | KMT2A (0.43) | ALDH1A1TSHRESR1 | |
| SCHEMBL9319730 | 0.75 | ALDH1A1 (0.48) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL27988192 | 0.74 | ALDH1A1 (0.52) | ALDH1A1TSHRS1PR2S1PR4S1PR1 | |
| SCHEMBL18817977 | 0.72 | SPHK1 (0.37) | TSHRCA1CA2SPHK1 | |
| SCHEMBL21178019 | 0.72 | SPHK1 (0.37) | TSHRCA1CA2SPHK1 | |
| SCHEMBL20709888 | 0.72 | SPHK1 (0.37) | TSHRCA1CA2SPHK1 | |
| SCHEMBL31465182 | 0.72 | SPHK1 (0.37) | TSHRCA1CA2SPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114026234-A | Antisense oligonucleotides altering DUX4pre-mRNA splicing | 第一三共株式会社 | 2022-02-08 | — | — | CN | disclosed |