Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019618 | 1.00 | PDE4D (0.44) | PDE4DKDM4EMAPTALDH1A1MAOA | |
| SCHEMBL9573042 | 0.94 | ACHE (0.41) | PDE4DKDM4EMAPTALDH1A1MAOA | |
| Hydrochloric Acid SCHEMBL11547300 | 0.92 | ACHE (0.40) | PDE4DKDM4EMAPTGAALMNA | |
| SCHEMBL31268130 | 0.89 | MAOA (0.47) | KDM4EMAPTALDH1A1MAOAGLA | |
| SCHEMBL17144907 | 0.89 | MAOA (0.47) | KDM4EMAPTALDH1A1MAOAGLA | |
| SCHEMBL251439 | 0.89 | MAOA (0.47) | KDM4EMAPTALDH1A1MAOAGLA | |
| SCHEMBL16973461 | 0.88 | ALDH1A1 (0.41) | PDE4DKDM4EMAPTALDH1A1MAOA | |
| Hydrochloric Acid SCHEMBL4772044 | 0.87 | MAOA (0.46) | KDM4EMAPTALDH1A1MAOAGLA | |
| Hydrochloric Acid SCHEMBL5006407 | 0.85 | MAOA (0.45) | KDM4EMAPTALDH1A1MAOAGLA | |
| SCHEMBL19932799 | 0.84 | KDM4E (0.40) | KDM4EMAPTALDH1A1MAOAGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115260094-B | New method for synthesizing norlinderane hydrochloride | 珠海润都制药股份有限公司 | 2024-04-05 | — | — | CN | disclosed |
| CN-115260094-A | Novel synthetic method of higenamine hydrochloride | 珠海润都制药股份有限公司 | 2022-11-01 | — | — | CN | disclosed |