SCHEMBL28933698

SCHEMBL28933698

O=C(NC(=O)c1c(F)cccc1F)Nc1cc(Cl)c(OC(F)(F)C(F)(F)C(F)F)cc1Cl

nearest known ligand 0.76

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 4/20 0.76
MEN1 O00255 3/20 0.76
MAPT P10636 2/20 0.76
USP2 O75604 1/20 0.76
ALOX15 P16050 1/20 0.76
POLB P06746 1/20 0.48
ATM Q13315 1/20 0.45
KDM4E B2RXH2 3/20 0.38
ALDH1A1 P00352 2/20 0.38
TLR7 Q9NYK1 1/20 0.37
GAA P10253 2/20 0.37
TDP1 Q9NUW8 2/20 0.37
THRB P10828 1/20 0.37
RECQL P46063 1/20 0.37
PYGL P06737 3/20 0.37
TRPV1 Q8NER1 1/20 0.36
NPC1 O15118 1/20 0.36
MAPK1 P28482 1/20 0.36
IL2 P60568 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7587434 0.91 KMT2A (0.88) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL10402381 0.89 KMT2A (0.76) KMT2AMEN1MAPTUSP2ALOX15
Lufenuron SCHEMBL29850969 0.87 KMT2A (1.00) KMT2AMEN1MAPTUSP2ALOX15
Lufenuron SCHEMBL27105 0.87 KMT2A (1.00) KMT2AMEN1MAPTUSP2ALOX15
Lufenuron SCHEMBL28709254 0.87 KMT2A (1.00) KMT2AMEN1MAPTUSP2ALOX15
Lufenuron SCHEMBL4131569 0.87 KMT2A (1.00) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL7591855 0.87 KMT2A (0.85) KMT2AMEN1MAPTUSP2ALOX15
Lufenuron SCHEMBL15555900 0.87 KMT2A (1.00) KMT2AMEN1MAPTUSP2ALOX15
Lufenuron SCHEMBL29350147 0.87 KMT2A (1.00) KMT2AMEN1MAPTUSP2ALOX15
SCHEMBL7585954 0.86 KMT2A (0.83) KMT2AMEN1MAPTUSP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114163356-B Preparation method of urea pesticide lufenuron 江苏中旗科技股份有限公司 2023-06-06 CN claimed
CN-117770263-A Mite-killing composition and application thereof 江西海阔利斯生物科技有限公司 2024-03-29 CN disclosed
CN-117397693-A Acaricide and application thereof 青岛凯源祥化工有限公司 2024-01-16 CN disclosed
CN-114163356-B Preparation method of urea pesticide lufenuron 江苏中旗科技股份有限公司 2023-06-06 CN disclosed
CN-116035021-A Insecticidal composition containing fenoxycarb and lufenuron, preparation method and application 江西田友生化有限公司 2023-05-02 CN disclosed
CN-114163356-A Preparation method of carbamide pesticide lufenuron 江苏中旗科技股份有限公司 2022-03-11 CN disclosed