SCHEMBL28934022

SCHEMBL28934022

O=C=NC[PH](=O)Cc1ccccc1

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 5/20 0.35
ALDH1A1 P00352 3/20 0.35
TRPA1 O75762 2/20 0.35
CYP3A4 P08684 1/20 0.35
HPGD P15428 1/20 0.35
CYP2E1 P05181 1/20 0.33
CYP2A6 P11509 1/20 0.33
HIF1A Q16665 1/20 0.33
CYP2A13 Q16696 1/20 0.33
EPAS1 Q99814 1/20 0.33
F2 P00734 1/20 0.32
PLG P00747 1/20 0.32
ELANE P08246 1/20 0.32
CTSG P08311 1/20 0.32
CMA1 P23946 1/20 0.32
CTRC Q99895 1/20 0.32
MAOB P27338 1/20 0.32
CALM1 P0DP23 1/20 0.31
TSHR P16473 1/20 0.30
EPHX2 P34913 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1322 0.76 MAOB (0.46) ALDH1A1TRPA1HPGDF2PLG
SCHEMBL1172136 0.74 MIF (0.60) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL1330511 0.74 MIF (0.60) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL5966 0.74 MIF (0.60) MIFALDH1A1TRPA1CYP3A4HPGD
Phosphonic Acid SCHEMBL1162434 0.74 TRPA1 (0.50) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL28983345 0.74 MIF (0.54) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL28217842 0.74 MIF (0.54) MIFALDH1A1TRPA1CYP3A4HPGD
Hydrogen Sulfide SCHEMBL2772168 0.73 MIF (0.58) MIFALDH1A1TRPA1CYP3A4HPGD
Ammonia Solution, Strong SCHEMBL8901629 0.73 MIF (0.58) MIFALDH1A1TRPA1CYP3A4HPGD
Cyanide SCHEMBL28125462 0.69 ALDH1A1 (0.54) MIFALDH1A1TRPA1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113372388-A Method for preparing isocyanate containing P-C bond based on liquid phase thermal cracking 湖北民族大学 2021-09-10 CN disclosed