Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL8901629

N.O=C=NCc1ccccc1

nearest known ligand 0.58

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 4/20 0.58
ALDH1A1 P00352 3/20 0.58
TRPA1 O75762 2/20 0.58
CYP3A4 P08684 1/20 0.58
HPGD P15428 1/20 0.58
CYP2E1 P05181 1/20 0.39
CYP2A6 P11509 1/20 0.39
HIF1A Q16665 1/20 0.39
CYP2A13 Q16696 1/20 0.39
EPAS1 Q99814 1/20 0.39
GRIN1 Q05586 2/20 0.38
GRIN2B Q13224 2/20 0.38
NOS2 P35228 1/20 0.38
CALM1 P0DP23 1/20 0.38
SCN2A Q99250 1/20 0.37
TSHR P16473 2/20 0.36
EPHX2 P34913 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
AKR1B1 P15121 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1172136 0.98 MIF (0.60) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL1330511 0.98 MIF (0.60) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL5966 0.98 MIF (0.60) MIFALDH1A1TRPA1CYP3A4HPGD
Hydrogen Sulfide SCHEMBL2772168 0.95 MIF (0.58) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL28217842 0.91 MIF (0.54) MIFALDH1A1TRPA1CYP3A4HPGD
Cyanide SCHEMBL28125462 0.91 ALDH1A1 (0.54) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL28983345 0.91 MIF (0.54) MIFALDH1A1TRPA1CYP3A4HPGD
Butane SCHEMBL27917654 0.89 ALDH1A1 (0.52) MIFALDH1A1TRPA1CYP3A4HPGD
SCHEMBL1162533 0.89 TRPA1 (0.52) MIFALDH1A1TRPA1CYP3A4HPGD
Benzylamine SCHEMBL25166822 0.87 LOXL2 (0.56) MIFALDH1A1TRPA1CYP3A4HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1997024328-A1 2-AMINO-HETEROCYCLES AND THERAPEUTIC USES THEREFOR BAYER AKTIENGESELLSCHAFT (DE) 1997-07-10 WO disclosed