Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 4/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KRAS | P01116 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28934408 | 0.90 | USP2 (0.34) | MAPTKDM4ETLR9MEN1KMT2A | |
| SCHEMBL28934542 | 0.88 | MAPT (0.39) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL28934596 | 0.85 | L3MBTL1 (0.37) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL28934464 | 0.82 | MAPT (0.40) | MAPTMEN1KMT2AALDH1A1NPSR1 | |
| SCHEMBL28934452 | 0.80 | MAPT (0.39) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28934436 | 0.78 | ACHE (0.41) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28934710 | 0.78 | ACHE (0.41) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28934449 | 0.78 | KDM4E (0.40) | MAPTKDM4ETLR9MEN1KMT2A | |
| SCHEMBL30108834 | 0.77 | G6PD (0.44) | MAPTKDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL28934496 | 0.74 | PDE5A (0.46) | MAPTMEN1KMT2AALDH1A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |