Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24379631 | 1.00 | NSD2 (0.35) | NSD2MAPK1KDM4EHTTGLA | |
| SCHEMBL30932816 | 1.00 | NSD2 (0.35) | NSD2MAPK1KDM4EHTTGLA | |
| SCHEMBL587789 | 0.97 | MAPK1 (0.37) | NSD2MAPK1KDM4EHTTGLA | |
| SCHEMBL581560 | 0.90 | MAPK1 (0.32) | NSD2MAPK1KDM4EACHEMEN1 | |
| SCHEMBL30932858 | 0.82 | NSD2 (0.31) | NSD2MAPK1 | |
| SCHEMBL13534296 | 0.82 | ACHE (0.34) | NSD2MAPK1ACHEMEN1KMT2A | |
| SCHEMBL1205725 | 0.77 | GOT1 (0.41) | KDM4E | |
| SCHEMBL6932370 | 0.77 | ALDH1A1 (0.33) | KDM4EHTTGLA | |
| SCHEMBL13534066 | 0.76 | ACHE (0.33) | MAPK1ACHEMEN1KMT2A | |
| SCHEMBL30932856 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118234711-A | Cyclopyridazine compounds | 尼科治疗有限公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-115433163-A | NLRP3 inflammasome inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2022-12-06 | — | — | CN | disclosed |