Methane

Methane

SCHEMBL28935271

C.CCOC(=O)C(c1ccccc1)c1ccc(O)cc1

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.53
CYP1A2 P05177 1/20 0.53
CYP2D6 P10635 1/20 0.53
CHRM1 P11229 4/20 0.51
CHRM3 P20309 4/20 0.51
CHRM2 P08172 3/20 0.51
CHRM4 P08173 3/20 0.51
HSD17B10 Q99714 1/20 0.51
ALDH1A1 P00352 2/20 0.51
CYP3A4 P08684 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 1/20 0.50
MMP8 P22894 1/20 0.50
CNR1 P21554 1/20 0.48
CNR2 P34972 1/20 0.48
CA12 O43570 1/20 0.47
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
ESR1 P03372 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27965729 0.98 LMNA (0.54) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL1395571 0.91 CA12 (0.55) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL2310025 0.89 LMNA (0.62) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL5084136 0.86 LMNA (0.55) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL29299736 0.84 L3MBTL1 (0.50) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL29299737 0.83 LMNA (0.53) LMNACYP1A2CYP2D6CHRM1CHRM3
Methane SCHEMBL28696266 0.83 KMT2A (0.56) LMNACHRM1CHRM3CHRM2CHRM4
SCHEMBL28713490 0.83 LMNA (0.56) LMNACYP1A2CYP2D6CHRM1CHRM3
SCHEMBL2843638 0.81 KMT2A (0.58) LMNACHRM1CHRM3CHRM2CHRM4
SCHEMBL27965914 0.81 L3MBTL1 (0.50) LMNACYP1A2CYP2D6CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110431177-B Curable composition, in particular as primer for the adhesion of crystalline rubbers to substrates 汉高股份有限及两合公司 2022-03-01 CN disclosed