Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.54 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.54 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KLK7 | P49862 | 2/20 | 0.49 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2310025 | 0.93 | LMNA (0.62) | LMNACYP1A2CYP2D6CHRM1CHRM3 | |
| SCHEMBL3541681 | 0.93 | MEN1 (0.49) | LMNACYP1A2CYP2D6CHRM1CHRM3 | |
| SCHEMBL27965729 | 0.88 | LMNA (0.54) | LMNACYP1A2CYP2D6CHRM1CHRM3 | |
| Methane SCHEMBL28935271 | 0.86 | LMNA (0.53) | LMNACYP1A2CYP2D6CHRM1CHRM3 | |
| SCHEMBL29299737 | 0.86 | LMNA (0.53) | LMNACYP1A2CYP2D6CHRM1CHRM3 | |
| SCHEMBL29299753 | 0.85 | L3MBTL1 (0.51) | LMNACYP1A2CYP2D6CHRM1CHRM3 | |
| SCHEMBL28093888 | 0.84 | KMT2A (0.58) | LMNACHRM1CHRM3CHRM2CHRM4 | |
| SCHEMBL4647971 | 0.83 | TSHR (0.51) | LMNACYP1A2CYP2D6CHRM1CHRM3 | |
| SCHEMBL4534323 | 0.83 | CYP1A2 (0.53) | LMNACYP1A2CYP2D6CHRM1CHRM3 | |
| SCHEMBL17583661 | 0.82 | CYP2D6 (0.52) | LMNACYP1A2CYP2D6CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080221350-A1 | Process for Preparing 2-Arylcarbonyl Compounds, 2-Aryl Esters and 2-Arylnitriles and their Heteroaromatic Analogues | ARCHIMICA GMBH (DE) | 2008-09-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080221350-A1 | Process for Preparing 2-Arylcarbonyl Compounds, 2-Aryl Esters and 2-Arylnitriles and their Heteroaromatic Analogues | SMARCC2, FES, SNCA | LMNA 1717/4885CYP1A2 1301/4885CYP2D6 1663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.