Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 2/20 | 0.37 |
| ▸ | SPR | P35270 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | DDR2 | Q16832 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | MAP3K20 | Q9NYL2 | 1/20 | 0.35 |
| ▸ | MAP3K2 | Q9Y2U5 | 1/20 | 0.35 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.34 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1406966 | 0.83 | MAPT (0.51) | ALDH1A1KDM4EHSD11B1MAPTSMN1; SMN2 | |
| Potassium SCHEMBL31133556 | 0.82 | MAPT (0.50) | ALDH1A1KDM4EHSD11B1SPRMAPT | |
| SCHEMBL28613582 | 0.82 | MAPT (0.50) | ALDH1A1KDM4EHSD11B1MAPTSMN1; SMN2 | |
| Potassium Ion SCHEMBL21818753 | 0.81 | MAPT (0.36) | ALDH1A1KDM4EHSD11B1SPRMAPT | |
| SCHEMBL1406856 | 0.79 | HSD11B1 (0.61) | HSD11B1 | |
| SCHEMBL1407022 | 0.78 | POLB (0.47) | ALDH1A1KDM4EHSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL1407020 | 0.78 | POLB (0.47) | ALDH1A1KDM4EHSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL30153839 | 0.78 | ACHE (0.40) | ALDH1A1KDM4ESPRPOLBMPO | |
| SCHEMBL1407186 | 0.78 | POLB (0.47) | ALDH1A1KDM4EHSD11B1MAPTSMN1; SMN2 | |
| SCHEMBL23626199 | 0.78 | SPR (0.53) | ALDH1A1KDM4EHSD11B1SPRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114181150-A | Pyrazole amide derivative, preparation method and application thereof | 沈阳万菱生物技术有限公司 | 2022-03-15 | — | — | CN | disclosed |