Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30781427 | 0.76 | SCN4A (0.34) | — | |
| SCHEMBL27148216 | 0.76 | SCN4A (0.34) | — | |
| SCHEMBL29444432 | 0.76 | EGFR (0.34) | DGAT1 | |
| SCHEMBL28694286 | 0.76 | EGFR (0.34) | DGAT1 | |
| SCHEMBL30994361 | 0.75 | LPL (0.33) | — | |
| SCHEMBL31716120 | 0.75 | EGFR (0.31) | — | |
| SCHEMBL25290017 | 0.75 | — | — | |
| SCHEMBL31083451 | 0.75 | — | — | |
| SCHEMBL25251795 | 0.75 | UCHL1 (0.31) | — | |
| SCHEMBL25250802 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057759-B | Fused tetracyclic derivative, preparation method thereof and application thereof in medicines | 江苏恒瑞医药股份有限公司 | 2023-05-16 | — | — | CN | disclosed |
| CN-114057759-A | Condensed tetracyclic derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-02-18 | — | — | CN | disclosed |