Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28694286 | 1.00 | EGFR (0.34) | EGFRUCHL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16815751 | 0.88 | EGFR (0.39) | EGFRUCHL1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL22124100 | 0.84 | EGFR (0.36) | EGFRUCHL1DGAT1 | |
| SCHEMBL22320285 | 0.78 | ACHE (0.33) | EGFRUCHL1 | |
| SCHEMBL30229151 | 0.78 | TTK (0.32) | EGFRUCHL1DGAT1 | |
| SCHEMBL19491485 | 0.77 | DGAT1 (0.33) | EGFRUCHL1DGAT1 | |
| SCHEMBL31753982 | 0.77 | EGFR (0.36) | EGFR | |
| SCHEMBL24046844 | 0.76 | SLC6A2 (0.42) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28935339 | 0.76 | DGAT1 (0.30) | DGAT1 | |
| SCHEMBL19087000 | 0.75 | CSF1R (0.34) | EGFRUCHL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114057759-A | Condensed tetracyclic derivative, preparation method and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2022-02-18 | — | — | CN | disclosed |