SCHEMBL289355

SCHEMBL289355

CCCCCc1cccc(C(CC)C(=O)O)c1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 5/20 0.50
PPARG P37231 3/20 0.50
KDM4A O75164 1/20 0.48
LPL P06858 2/20 0.48
LIPG Q9Y5X9 2/20 0.48
CYSLTR2 Q9NS75 1/20 0.46
CYSLTR1 Q9Y271 1/20 0.46
KAT8 Q9H7Z6 2/20 0.44
ALDH1A1 P00352 1/20 0.44
AKR1C3 P42330 1/20 0.43
AKR1C2 P52895 1/20 0.43
AKR1C1 Q04828 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL290161 0.90 PPARA (0.49) PPARAPPARGLPLLIPGCYSLTR2
SCHEMBL28025268 0.89 PPARA (0.48) PPARAPPARGLPLLIPGCYSLTR2
SCHEMBL17571629 0.86 PPARA (0.46) PPARAPPARGLPLLIPGCYSLTR2
SCHEMBL4390456 0.85 AKR1C3 (0.46) KDM4AAKR1C3AKR1C2AKR1C1
SCHEMBL30375642 0.85 PPARA (0.52) PPARAPPARGLPLLIPGCYSLTR2
SCHEMBL290381 0.84 PPARA (0.51) PPARAPPARGLPLLIPGCYSLTR2
SCHEMBL4389616 0.84 NOS1 (0.45) KDM4AAKR1C3AKR1C2AKR1C1
SCHEMBL16050558 0.82 PPARA (0.50) PPARAPPARGLPLLIPGCYSLTR2
SCHEMBL11498518 0.82 PPARA (0.50) PPARAPPARGLPLLIPGCYSLTR2
SCHEMBL10525905 0.80 CYSLTR2 (0.56) CYSLTR2CYSLTR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120095102-A1 Salts of 3-Pentylphenylacetic Acid and Pharmaceutical Uses Thereof PROMETIC PHARMA SMT LIMITED (GB) 2012-04-19 US claimed
EP-2427417-A1 SALTS OF 3-PENTYLPHENYLACETIC ACID AND PHARMACEUTICAL USES THEREOF ProMetic BioSciences Inc. (CA) 2012-03-14 EP claimed
US-20120095102-A1 Salts of 3-Pentylphenylacetic Acid and Pharmaceutical Uses Thereof PROMETIC PHARMA SMT LIMITED (GB) 2012-04-19 US disclosed
EP-2427417-A1 SALTS OF 3-PENTYLPHENYLACETIC ACID AND PHARMACEUTICAL USES THEREOF ProMetic BioSciences Inc. (CA) 2012-03-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120095102-A1 Salts of 3-Pentylphenylacetic Acid and Pharmaceutical Uses Thereof GLS, REN, PTP4A3 PPARA 305/4885PPARG 864/4885KDM4A 3306/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.