SCHEMBL2893576

SCHEMBL2893576

CC(C)(C)NS(=O)(=O)c1ccccc1I

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 2/20 0.50
MAPT P10636 2/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
KDM4E B2RXH2 1/20 0.46
MEN1 O00255 1/20 0.46
NPC1 O15118 1/20 0.46
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
RAB9A P51151 1/20 0.46
KMT2A Q03164 1/20 0.46
PARG Q86W56 1/20 0.45
ALOX5AP P20292 10/20 0.41
FEN1 P39748 10/20 0.41
ALDH1A1 P00352 2/20 0.41
ITGAV P06756 1/20 0.39
HTR1A P08908 1/20 0.38
HTR7 P34969 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2803354 0.85 NSD2 (0.58) NSD2MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL4177585 0.79 CYP1A2 (0.47) SMN1; SMN2LMNAALOX5APFEN1ALDH1A1
SCHEMBL29321430 0.79 ITGAV (0.43) MAPTALDH1A1ITGAVHTR1AHTR7
Water SCHEMBL27570164 0.78 NSD2 (0.49) NSD2MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL18077893 0.78 NSD2 (0.57) NSD2MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL23345388 0.78 NSD2 (0.51) NSD2MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL634084 0.78 NSD2 (0.51) NSD2MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL13075810 0.78 NSD2 (0.51) NSD2MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL264098 0.76 CA1 (0.52) NSD2MAPTSMN1; SMN2KDM4EMEN1
SCHEMBL3404809 0.76 NSD2 (0.69) NSD2MAPTSMN1; SMN2KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP claimed
US-7855166-B2 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2010-12-21 US disclosed
US-20100285964-A1 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3, 5-TRIAZINE-2-YL) CARBAMOYL] BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYERCROPSCIENCE AG (DE) 2010-11-11 US disclosed
US-20100285964-A1 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3, 5-TRIAZINE-2-YL) CARBAMOYL] BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYERCROPSCIENCE AG (DE) 2010-11-11 US disclosed
US-20100285964-A1 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3, 5-TRIAZINE-2-YL) CARBAMOYL] BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYERCROPSCIENCE AG (DE) 2010-11-11 US disclosed
EP-2205091-A2 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3,5-TRIAZINE-2-YL)CARBAMOYL]BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS Bayer CropScience AG (DE) 2010-07-14 EP disclosed
WO-2009053058-A2 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3,5-TRIAZINE-2-YL)CARBAMOYL]BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2009-04-30 WO disclosed
WO-2009053058-A2 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3,5-TRIAZINE-2-YL)CARBAMOYL]BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2009-04-30 WO disclosed
EP-2052604-A1 Salts of 2-lodo-N-[(4-methoxy-6-methyl-1,3,5-triazin-2-yl)carbamoyl] benzol sulphonamide, method for its manufacture and its application as herbicide and plant growth regulator Bayer CropScience AG (DE) 2009-04-29 EP disclosed
EP-1877380-A1 SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2008-01-16 EP disclosed
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds BAYER CROPSCIENCE GMBH (DE) 2006-11-16 US disclosed
EP-1717228-A1 Sulfonylamino(thio)carbonylderivatives as herbicides or plant growth regulators Bayer CropScience GmbH (DE) 2006-11-02 EP disclosed
WO-2006114221-A1 SULFONYLAMINO(THIO)CARBONYL COMPOUNDS IN THE FORM OF HERBICIDES OR PLANT GROWTH REGULATORS BAYER CROPSCIENCE AG (DE) 2006-11-02 WO disclosed
EP-0516392-B1 Naphthyridine derivatives as angiotensin II inhibitors ASTRAZENECA AB (SE) 2001-08-29 EP disclosed
US-5294620-A Hypotensive agents or compounds for cardiovascular disorders IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1994-03-15 US disclosed
US-5217976-A Hypotensive agents, congestive heart failure IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-06-08 US disclosed
EP-0516392-A2 Naphthyridine derivatives as angiotensin II inhibitors ZENECA LIMITED (GB) 1992-12-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100285964-A1 SALTS OF 2-IODO-N-[(4-METHOXY-6-METHYL-1,3, 5-TRIAZINE-2-YL) CARBAMOYL] BENZENESULFONAMIDE, METHOD FOR THE PRODUCTION THEREOF AND USE THEREOF AS HERBICIDES AND PLANT GROWTH REGULATORS MYB, INMT, AS3MT NSD2 49/4885MAPT 4121/4885SMN1; SMN2 4069/4885
US-20060258536-A1 Sulfonylamino(thio)carbonyl compounds TST, CBR3, MYB NSD2 2595/4885MAPT 3054/4885SMN1; SMN2 4458/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.