SCHEMBL28935787

SCHEMBL28935787

CC(C)(C)N(C(=O)O)c1scnc1Br

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.33
PKM P14618 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27856737 0.74 KDM4E (0.32) KDM4EPKM
SCHEMBL16774585 0.70 KDM4E (0.33) KDM4EPKM
SCHEMBL28935626 0.68 HDAC3 (0.36)
SCHEMBL17473769 0.68 KDM4E (0.31) KDM4E
SCHEMBL2353201 0.67
SCHEMBL2898172 0.67 KDM4E (0.36) KDM4E
SCHEMBL702921 0.67 GRM5 (0.32)
SCHEMBL149840 0.67 SMN1; SMN2 (0.34) PKM
SCHEMBL5582871 0.66 KDM4E (0.36) KDM4E
SCHEMBL2890584 0.66 ALDH1A1 (0.40) PKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611895-A Arylamino derivative estrogen receptor modulators and uses thereof 四川海思科制药有限公司 2023-01-17 CN disclosed