SCHEMBL28935802

SCHEMBL28935802

CCOP(=O)(C(=O)c1ccccc1)c1ccc(OC)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.49
CES1 P23141 1/20 0.49
NPC1 O15118 4/20 0.47
RAB9A P51151 4/20 0.47
LMNA P02545 2/20 0.45
ALDH1A1 P00352 1/20 0.45
ACHE P22303 1/20 0.45
KMT2A Q03164 2/20 0.44
PTGS2 P35354 1/20 0.44
MEN1 O00255 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
ADAM17 P78536 3/20 0.43
MAPT P10636 2/20 0.43
MMP1 P03956 2/20 0.43
MMP3 P08254 2/20 0.43
MMP9 P14780 2/20 0.43
PKM P14618 1/20 0.43
CDK5 Q00535 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28935780 0.94 CES2 (0.49) CES2CES1NPC1RAB9ALMNA
SCHEMBL3156328 0.88 LMNA (0.55) LMNAALDH1A1ACHEKMT2AMEN1
SCHEMBL10092167 0.79 MEN1 (0.54) CES2CES1NPC1RAB9ALMNA
SCHEMBL29582409 0.76 KMT2A (0.57) LMNAALDH1A1KMT2AMEN1HPGD
SCHEMBL4609622 0.75 MAPT (0.58) CES2CES1NPC1RAB9ALMNA
SCHEMBL11614997 0.75 KMT2A (0.56) NPC1RAB9AALDH1A1ACHEKMT2A
SCHEMBL7624317 0.74 ALDH1A1 (0.48) LMNAALDH1A1ACHEKMT2AMEN1
SCHEMBL18040244 0.73 POLB (0.49) CES2CES1NPC1RAB9ALMNA
SCHEMBL425583 0.73 NR1I2 (0.54) CES2CES1NPC1LMNAALDH1A1
SCHEMBL14981920 0.73 TSHR (0.49) CES2CES1NPC1LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115611940-A Method for preparing acylphosphine oxide photoinitiator and co-producing substituted oxetane compounds 常州强力先端电子材料有限公司 2023-01-17 CN disclosed