Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29919738 | 1.00 | TSHR (0.47) | TSHRALDH1A1KDM4ELMNAGLA | |
| SCHEMBL28936237 | 0.83 | ALDH1A1 (0.53) | TSHRALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL20187440 | 0.79 | KDM4E (0.51) | ALDH1A1KDM4ELMNAMAPK1MAPT | |
| SCHEMBL15942898 | 0.73 | L3MBTL1 (0.47) | ALDH1A1KDM4ELMNASMN1; SMN2 | |
| SCHEMBL1961297 | 0.72 | AGTR1 (0.45) | TSHRALDH1A1KDM4ELMNAGLA | |
| SCHEMBL1687176 | 0.69 | ALDH1A1 (0.45) | ALDH1A1KDM4ELMNAMAPTTP53 | |
| SCHEMBL3676351 | 0.69 | PDE4D (0.53) | TSHRALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL21393838 | 0.69 | MAPT (0.44) | TSHRALDH1A1KDM4ELMNAGLA | |
| SCHEMBL11811309 | 0.69 | KDM4E (0.48) | TSHRALDH1A1KDM4ELMNAPRKCZ | |
| SCHEMBL12590801 | 0.68 | CYP1A2 (0.42) | ALDH1A1KDM4ELMNAMAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109020957-B | Heterocyclic compounds as MNK inhibitors | 南京天印健华医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |