Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.35 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.35 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.35 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30680199 | 0.89 | JAK2 (0.42) | MAPTPRKCZRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL28936359 | 0.82 | OPRM1 (0.36) | MEN1KMT2A | |
| SCHEMBL30680173 | 0.77 | OPRM1 (0.37) | MEN1KMT2A | |
| SCHEMBL1769341 | 0.67 | LMNA (0.64) | MAPTSMN1; SMN2MEN1CYP1A2CYP3A4 | |
| SCHEMBL12273135 | 0.65 | LMNA (0.68) | MAPTSMN1; SMN2MEN1CYP1A2CYP3A4 | |
| SCHEMBL29126850 | 0.65 | MAPT (0.44) | MAPTPRKCZRAB9ASMN1; SMN2KMT2A | |
| SCHEMBL27541726 | 0.63 | MAPT (0.52) | MAPTPRKCZRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL2818552 | 0.63 | PRKCZ (0.41) | MAPTPRKCZRAB9ASMN1; SMN2MEN1 | |
| SCHEMBL16423615 | 0.63 | LMNA (0.58) | MAPTSMN1; SMN2MEN1CYP1A2CYP3A4 | |
| SCHEMBL6737966 | 0.63 | OPRM1 (0.67) | MAPTSMN1; SMN2MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117222640-A | Heterocyclic compounds as FGFR inhibitors and uses thereof | 先声再明医药有限公司 | 2023-12-12 | — | — | CN | disclosed |