Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.44 |
| ▸ | DRD5 | P21918 | 1/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937129 | 0.88 | HTR1F (0.62) | HTR1FMAPTRXFP1MEN1KMT2A | |
| SCHEMBL28937149 | 0.85 | HTR1F (0.61) | HTR1FMEN1KMT2ATP53NPC1 | |
| SCHEMBL23702725 | 0.84 | HTR1F (0.60) | HTR1FMAPTMEN1KMT2ATP53 | |
| SCHEMBL28937134 | 0.81 | MAPT (0.64) | HTR1FMAPTRXFP1MEN1KMT2A | |
| SCHEMBL1197324 | 0.80 | HTR1F (0.56) | HTR1FMEN1KMT2ATP53NPC1 | |
| SCHEMBL28808156 | 0.80 | HTR1F (0.56) | HTR1FMEN1KMT2ATP53NPC1 | |
| SCHEMBL28963589 | 0.79 | MAPT (0.61) | HTR1FMAPTTP53NPC1CYP1A2 | |
| SCHEMBL30908910 | 0.76 | HTR1F (0.77) | HTR1FCHRM5DRD5HTR1DHTR1E | |
| SCHEMBL21770996 | 0.76 | HTR1F (1.00) | HTR1FTP53CHRM5DRD5HTR1D | |
| SCHEMBL2537931 | 0.76 | HTR1F (0.77) | HTR1FCHRM5DRD5HTR1DHTR1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272425-B | Pyridyloxyl octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |