Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.62 |
| ▸ | SORT1 | Q99523 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.50 |
| ▸ | IDH1 | O75874 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | GRM5 | P41594 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937124 | 0.88 | HTR1F (0.61) | HTR1FMAPTALDH1A1GRM5RXFP1 | |
| SCHEMBL28937119 | 0.86 | HTR1F (0.63) | HTR1FSORT1MAPTCYP11B2ALDH1A1 | |
| SCHEMBL28808136 | 0.81 | HTR1F (0.57) | HTR1FSORT1MAPTCYP11B2ALDH1A1 | |
| SCHEMBL28937139 | 0.80 | RXFP1 (0.71) | HTR1FMAPTALDH1A1GRM5RXFP1 | |
| SCHEMBL935048 | 0.79 | GRM5 (0.52) | IDH1ALDH1A1GRM5NPC1MRGPRX4 | |
| SCHEMBL28937138 | 0.78 | HTR1F (0.58) | HTR1FMAPTIDH1ALDH1A1GRM5 | |
| SCHEMBL21771022 | 0.77 | HTR1F (1.00) | HTR1FSORT1CYP11B2NPC1RAB9A | |
| SCHEMBL16317363 | 0.77 | F10 (0.57) | CYP11B2ALDH1A1RXFP1NPC1RAB9A | |
| SCHEMBL23702725 | 0.77 | HTR1F (0.60) | HTR1FMAPTALDH1A1GRM5NPC1 | |
| SCHEMBL23528936 | 0.77 | HTR1F (0.75) | HTR1FSORT1CYP11B2ALDH1A1RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272425-B | Pyridyloxyl octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |