Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1F | P30939 | 2/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | SORT1 | Q99523 | 7/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.46 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SNCA | P37840 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28937119 | 0.86 | HTR1F (0.63) | HTR1FKDM4ELMNAMEN1KMT2A | |
| SCHEMBL28937124 | 0.85 | HTR1F (0.61) | HTR1FLMNAMEN1KMT2ANPC1 | |
| SCHEMBL28808156 | 0.83 | HTR1F (0.56) | HTR1FLMNAMEN1KMT2ASORT1 | |
| SCHEMBL1197324 | 0.83 | HTR1F (0.56) | HTR1FKDM4ELMNAMEN1KMT2A | |
| SCHEMBL23733275 | 0.83 | MEN1 (0.62) | HTR1FKDM4ELMNAMEN1KMT2A | |
| SCHEMBL28937159 | 0.80 | MEN1 (0.60) | HTR1FKDM4ELMNAMEN1KMT2A | |
| SCHEMBL23528955 | 0.79 | HTR1F (0.74) | HTR1FMEN1KMT2ANPC1TP53 | |
| SCHEMBL28947327 | 0.79 | HTR1F (0.80) | HTR1FMEN1KMT2ANPC1TP53 | |
| SCHEMBL29965342 | 0.77 | HTR1F (0.60) | HTR1FKDM4ELMNAMEN1KMT2A | |
| SCHEMBL28937144 | 0.77 | HTR1F (0.60) | HTR1FKDM4ELMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110272425-B | Pyridyloxyl octahydropyrrolo [3,4-c ] pyrrole derivatives and uses thereof | 广东东阳光药业有限公司 | 2022-11-04 | — | — | CN | disclosed |