Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OSBP | P22059 | 4/20 | 0.69 |
| ▸ | RORC | P51449 | 3/20 | 0.69 |
| ▸ | USP2 | O75604 | 2/20 | 0.69 |
| ▸ | CYP46A1 | Q9Y6A2 | 2/20 | 0.69 |
| ▸ | OSBP2 | Q969R2 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.69 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.61 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.58 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.58 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.58 |
| ▸ | NPC1L1 | Q9UHC9 | 2/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | FNTA | P49354 | 1/20 | 0.56 |
| ▸ | FNTB | P49356 | 1/20 | 0.56 |
| ▸ | CRYAB | P02511 | 1/20 | 0.55 |
| ▸ | HMGCR | P04035 | 1/20 | 0.55 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.55 |
| ▸ | ITGAV | P06756 | 1/20 | 0.55 |
| ▸ | SREBF2 | Q12772 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288702 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL336003 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL28750282 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL1917363 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL6390184 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL6387159 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL3350440 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL336002 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL22032772 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 | |
| SCHEMBL26642855 | 1.00 | OSBP (0.69) | OSBPRORCUSP2CYP46A1OSBP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478977-B | Polyurethane with side chain containing amino and preparation method thereof | 武汉科技大学 | 2023-06-02 | — | — | CN | claimed |
| CN-114478977-A | Polyurethane with amino-containing side chain and preparation method thereof | 武汉科技大学 | 2022-05-13 | — | — | CN | claimed |
| US-20250114377-A1 | TWO-PRONGED TREATMENT FOR NIEMANN PICK TYPE C DISEASE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2025-04-10 | — | — | US | disclosed |
| EP-4525880-A1 | TWO-PRONGED TREATMENT FOR NIEMANN PICK TYPE C DISEASE | University of Notre Dame du Lac (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-117897152-A | Nanoparticle compositions containing sugar-functionalized nucleic acid vectors | 蒂巴生物技术有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023225018-A1 | TWO-PRONGED TREATMENT FOR NIEMANN PICK TYPE C DISEASE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2023-11-23 | — | — | WO | disclosed |
| WO-2023172132-A1 | DHCR24 INHIBITORY COMPOUNDS | ACADEMISCH ZIEKENHUIS LEIDEN (h.o.d.n. LUMC) (NL) | 2023-09-14 | — | — | WO | disclosed |
| CN-114478977-B | Polyurethane with side chain containing amino and preparation method thereof | 武汉科技大学 | 2023-06-02 | — | — | CN | disclosed |
| CN-115702005-A | Vectors for efficient nucleic acid delivery | 蒂巴生物技术有限公司 | 2023-02-14 | — | — | CN | disclosed |
| CN-114478977-A | Polyurethane with amino-containing side chain and preparation method thereof | 武汉科技大学 | 2022-05-13 | — | — | CN | disclosed |
| US-11313866-B2 | Method of diagnosing and treating asphyxia | INFANDX AG (DE) | 2022-04-26 | — | — | US | disclosed |
| US-20010031874-A1 | Thiourea and benzamide compounds, compositions and methods of treating or preventing inflammatory diseases and atherosclerosis | CONNOR DAVID THOMAS (US) | 2001-10-18 | — | — | US | disclosed |
| US-20010018427-A1 | Method of using a scavenger receptor in the treatment of atherosclerosis | WARNER-LAMBERT COMPANY (US) | 2001-08-30 | — | — | US | disclosed |
| US-6268387-B1 | INHIBITORS OF THE ENZYME 15-LIPOXYGENASE AND ARE INHIBITORS OF MONOCYTE CHEMOTAXIS. | WARNER-LAMBERT COMPANY | 2001-07-31 | — | — | US | disclosed |
| EP-1063991-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY LLC (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-1042276-A1 | THIOUREA COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY LLC (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999047138-A1 | STATIN-MATRIX METALLOPROTEINASE INHIBITOR COMBINATIONS | WARNER-LAMBERT COMPANY (US) | 1999-09-23 | — | — | WO | disclosed |
| WO-1999032433-A1 | THIOUREA AND BENZAMIDE COMPOUNDS, COMPOSITIONS AND METHODS OF TREATING OR PREVENTING INFLAMMATORY DISEASES AND ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1999-07-01 | — | — | WO | disclosed |
| EP-0784681-A1 | METHOD OF USING A SCAVENGER RECEPTOR IN THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1997-07-23 | — | — | EP | disclosed |
| WO-1996011268-A1 | METHOD OF USING A SCAVENGER RECEPTOR IN THE TREATMENT OF ATHEROSCLEROSIS | WARNER-LAMBERT COMPANY (US) | 1996-04-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010031874-A1 | Thiourea and benzamide compounds, compositions and methods of treating or preventing inflammatory diseases and atherosclerosis | TPMT, CTH, CBS | OSBP 2033/4885RORC 2318/4885USP2 1754/4885 |
| US-20250114377-A1 | TWO-PRONGED TREATMENT FOR NIEMANN PICK TYPE C DISEASE | NPC1L1, NPC1, STING1 | OSBP 16/4885RORC 870/4885USP2 2106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.