SCHEMBL22032772

SCHEMBL22032772

CC(C)CCCC(C)[C@H]1CC[C@H]2[C@@H]3CC=C4C(O)[C@@H](O)CC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ OSBP P22059 4/20 0.69
▸ RORC P51449 3/20 0.69
▸ USP2 O75604 2/20 0.69
▸ CYP46A1 Q9Y6A2 2/20 0.69
▸ OSBP2 Q969R2 2/20 0.69
▸ LMNA P02545 1/20 0.69
▸ ABCB1 P08183 1/20 0.69
▸ SRD5A1 P18405 3/20 0.61
▸ GRIN1 Q05586 2/20 0.58
▸ GRIN2A Q12879 2/20 0.58
▸ NR1H3 Q13133 2/20 0.58
▸ NPC1L1 Q9UHC9 2/20 0.57
▸ POLA1 P09884 1/20 0.57
▸ FNTA P49354 1/20 0.56
▸ FNTB P49356 1/20 0.56
▸ CRYAB P02511 1/20 0.55
▸ HMGCR P04035 1/20 0.55
▸ ITGB3 P05106 1/20 0.55
▸ ITGAV P06756 1/20 0.55
▸ SREBF2 Q12772 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL288702 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL336003 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL28750282 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL289374 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL1917363 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL6390184 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL6387159 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL3350440 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL336002 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2
SCHEMBL26642855 1.00 OSBP (0.69) OSBPRORCUSP2CYP46A1OSBP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260078086-A1 VERSATILE BIODEGRADABLE MOLECULES AS NUCLEIC ACID CARRIERS TIBA BIOTECH LLC (US) 2026-03-19 — — US disclosed
US-20260069540-A1 GENE DELIVERY AGENTS TIBA BIOTECH LLC (US) 2026-03-12 — — US disclosed
US-20260014077-A1 NOVEL METHODS TO ENHANCE GENE DELIVERY TIBA BIOTECH LLC (US) 2026-01-15 — — US disclosed
EP-4667511-A2 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY Tiba Biotech LLC (US) 2025-12-24 — — EP disclosed
US-12491262-B2 Gene delivery agents TIBA BIOTECH LLC (US) 2025-12-09 — — US disclosed
US-20250354174-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS TIBA BIOTECH LLC (US) 2025-11-20 — — US disclosed
US-12410448-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TIBA BIOTECH LLC (US) 2025-09-09 — — US disclosed
US-20250144233-A1 NOVEL GENE DELIVERY AGENTS TIBA BIOTECH LLC 2025-05-08 — — US disclosed
WO-2025096681-A1 NOVEL GENE DELIVERY AGENTS TIBA BIOTECH LLC (US) 2025-05-08 — — WO disclosed
US-20240207187-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TIBA BIOTECH LLC (US) 2024-06-27 — — US disclosed
EP-4313170-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY Tiba Biotech LLC (US) 2024-02-07 — — EP disclosed
US-11859201-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TIBA BIOTECH LLC (US) 2024-01-02 — — US disclosed
US-20230310645-A1 NANOPARTICLE COMPOSITION FOR THE DELIVERY OF NUCLEIC ACID AGENTS TIBA BIOTECH LLC (US) 2023-10-05 — — US disclosed
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY TIBA BIOTECH LLC (US) 2023-05-18 — — US disclosed
US-20230100837-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS TIBA BIOTECH LLC (US) 2023-03-30 — — US disclosed
WO-2023022926-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS TIBA BIOTECH LLC (US) 2023-02-23 — — WO disclosed
EP-4132586-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY Tiba Biotech LLC (US) 2023-02-15 — — EP disclosed
WO-2022212838-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TIBA BIOTECH LLC (US) 2022-10-06 — — WO disclosed
EP-3890715-A1 THERAPEUTICS TARGETING MUTANT ADENOMATOUS POLYPOSIS COLI (APC) FOR THE TREATMENT OF CANCER The Board Of Regents Of The University Of Texas System (US) 2021-10-13 — — EP disclosed
WO-2020117972-A1 THERAPEUTICS TARGETING MUTANT ADENOMATOUS POLYPOSIS COLI (APC) FOR THE TREATMENT OF CANCER THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2020-06-11 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240207187-A1 DENDRITIC ARCHITECTURES AS NONVIRAL VECTORS IN GENE DELIVERY TLR3, TLR9, TLR6 OSBP 406/4885RORC 1514/4885USP2 3690/4885
US-12491262-B2 Gene delivery agents TSG101, TLR3, TLR9 OSBP 1539/4885RORC 2282/4885USP2 2366/4885
US-20250354174-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS TLR9, TLR3, TSG101 OSBP 3402/4885RORC 1597/4885USP2 3167/4885
US-20260069540-A1 GENE DELIVERY AGENTS LIPC, L3MBTL1, L3MBTL3 OSBP 833/4885RORC 2445/4885USP2 1837/4885
US-20230100837-A1 NANOPARTICLE COMPOSITIONS CONTAINING SUGAR FUNCTIONALIZED NUCLEIC ACID CARRIERS TLR9, TLR3, TSG101 OSBP 3402/4885RORC 1597/4885USP2 3167/4885
US-20250144233-A1 NOVEL GENE DELIVERY AGENTS TSG101, STING1, TLR3 OSBP 1594/4885RORC 2260/4885USP2 2342/4885
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY POLN, TLR9, TSG101 OSBP 3888/4885RORC 1994/4885USP2 3009/4885
US-12410448-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TLR9, TLR3, TSG101 OSBP 3402/4885RORC 1597/4885USP2 3167/4885
US-11859201-B2 Nanoparticle compositions containing sugar functionalized nucleic acid carriers TLR9, TLR3, TSG101 OSBP 3402/4885RORC 1597/4885USP2 3167/4885
US-20260014077-A1 NOVEL METHODS TO ENHANCE GENE DELIVERY LDLR, NPC1L1, LIPG OSBP 1252/4885RORC 754/4885USP2 2582/4885
US-20260078086-A1 VERSATILE BIODEGRADABLE MOLECULES AS NUCLEIC ACID CARRIERS NSUN2, SMC1A, SSU72 OSBP 267/4885RORC 4796/4885USP2 1427/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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