Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 13/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | CLK1 | P49759 | 1/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28714659 | 1.00 | FFAR1 (0.50) | FFAR1MTNR1ABACE1CTSDAPP | |
| SCHEMBL28716707 | 0.84 | FFAR1 (0.54) | FFAR1MTNR1AALDH1A1GAAMAPT | |
| SCHEMBL28720097 | 0.84 | FFAR1 (0.54) | FFAR1MTNR1AALDH1A1GAAMAPT | |
| SCHEMBL29444764 | 0.84 | MTNR1A (0.63) | FFAR1MTNR1APOLBALDH1A1GAA | |
| SCHEMBL6982719 | 0.84 | MTNR1A (0.63) | FFAR1MTNR1APOLBALDH1A1GAA | |
| SCHEMBL1870686 | 0.84 | MTNR1A (0.63) | FFAR1MTNR1APOLBALDH1A1GAA | |
| SCHEMBL11484008 | 0.79 | MTNR1A (0.56) | FFAR1MTNR1APOLBALDH1A1GAA | |
| SCHEMBL28723005 | 0.72 | FFAR1 (0.51) | FFAR1MAPT | |
| SCHEMBL28720094 | 0.72 | FFAR1 (0.48) | FFAR1MTNR1AALDH1A1LMNAMAPT | |
| SCHEMBL28716720 | 0.72 | FFAR1 (0.51) | FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092774-B | Aromatic propionic acid derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-04-08 | — | — | CN | disclosed |