Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.63 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1870686 | 1.00 | MTNR1A (0.63) | MTNR1AFFAR1MAPTGAAALOX5 | |
| SCHEMBL6982719 | 1.00 | MTNR1A (0.63) | MTNR1AFFAR1MAPTGAAALOX5 | |
| SCHEMBL11484008 | 0.94 | MTNR1A (0.56) | MTNR1AFFAR1MAPTGAAALOX5 | |
| SCHEMBL28716707 | 0.89 | FFAR1 (0.54) | MTNR1AFFAR1MAPTGAAALDH1A1 | |
| SCHEMBL28720097 | 0.89 | FFAR1 (0.54) | MTNR1AFFAR1MAPTGAAALDH1A1 | |
| SCHEMBL7199006 | 0.85 | MTNR1A (0.60) | MTNR1AFFAR1MAPTGAAALOX5 | |
| SCHEMBL9208736 | 0.85 | MTNR1A (0.60) | MTNR1AFFAR1MAPTGAAALOX5 | |
| SCHEMBL9206095 | 0.85 | MTNR1A (0.60) | MTNR1AFFAR1MAPTGAAALOX5 | |
| SCHEMBL28714659 | 0.84 | FFAR1 (0.50) | MTNR1AFFAR1MAPTGAAPOLB | |
| SCHEMBL28937417 | 0.84 | FFAR1 (0.50) | MTNR1AFFAR1MAPTGAAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110092774-B | Aromatic propionic acid derivative, preparation method and application thereof | 中国科学院上海药物研究所 | 2022-04-08 | — | — | CN | disclosed |