Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP1 | O94782 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.30 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5346745 | 0.85 | SMN1; SMN2 (0.37) | USP1ESR1ESR2 | |
| SCHEMBL464822 | 0.79 | CYP2C19 (0.47) | — | |
| SCHEMBL18865557 | 0.76 | POLB (0.44) | — | |
| SCHEMBL14394577 | 0.76 | ESR2 (0.48) | ESR1ESR2 | |
| SCHEMBL28362255 | 0.76 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL18865814 | 0.76 | CYP11B2 (0.38) | — | |
| SCHEMBL5351705 | 0.74 | NPC1 (0.35) | USP1ESR1ESR2 | |
| SCHEMBL5358838 | 0.73 | MEN1 (0.36) | — | |
| SCHEMBL273057 | 0.73 | KDM1A (0.43) | — | |
| SCHEMBL18865590 | 0.72 | HRH3 (0.35) | USP1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114702495-A | Purinones as ubiquitin-specific protease 1 inhibitors | 福马治疗有限公司 | 2022-07-05 | — | — | CN | disclosed |
| CN-108473495-B | Purinones as ubiquitin-specific protease 1 inhibitors | 福马治疗有限公司 | 2022-04-12 | — | — | CN | disclosed |