SCHEMBL464822

SCHEMBL464822

CC1(C)COC1c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
TSHR P16473 1/20 0.43
KDM1A O60341 4/20 0.42
MAOA P21397 4/20 0.42
MAOB P27338 4/20 0.42
ALDH1A1 P00352 3/20 0.41
CYP1A2 P05177 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2C9 P11712 1/20 0.37
CHRM2 P08172 2/20 0.36
CHRM4 P08173 2/20 0.36
CHRM5 P08912 2/20 0.36
CHRM1 P11229 2/20 0.36
CHRM3 P20309 2/20 0.36
SLC6A2 P23975 1/20 0.36
ADRA1A P35348 1/20 0.36
HTR2B P41595 1/20 0.36
SLC6A3 Q01959 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5346745 0.89 SMN1; SMN2 (0.37) CYP2C19MEN1KMT2AALDH1A1CYP1A2
SCHEMBL5358838 0.85 MEN1 (0.36) CYP2C19MEN1KMT2ATSHRKDM1A
SCHEMBL14394577 0.79 ESR2 (0.48) ALDH1A1
SCHEMBL28937620 0.79 USP1 (0.31)
SCHEMBL18865557 0.79 POLB (0.44) KMT2ATSHRKDM1AMAOBSLC6A2
SCHEMBL5351705 0.78 NPC1 (0.35) MEN1KMT2AKDM1A
SCHEMBL14394351 0.77 ESR1 (0.32) CYP2C19MEN1KMT2A
SCHEMBL273057 0.76 KDM1A (0.43) MEN1KMT2AKDM1AMAOAMAOB
SCHEMBL23781847 0.75 HTR2C (0.48) MEN1KMT2AKDM1ASLC6A2HTR2B
SCHEMBL14183320 0.75 MGLL (0.35) KDM1AALDH1A1CHRM2HTR2BHTR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1646493-B1 VISCOSITY REDUCIBLE RADIATION CURABLE RESIN COMPOSITION DSM IP ASSETS BV (NL) 2011-11-16 EP disclosed
EP-2301742-A1 Viscosity reducible radiation curable resin composition DSM IP Assets B.V. (NL) 2011-03-30 EP disclosed
CN-1826216-B Viscosity-reducible radiation-curable resin composition DSM IP ASSETS BV 2010-04-21 CN disclosed
EP-1551890-B1 CURABLE COMPOSITIONS AND RAPID PROTOTYPING PROCESS USING THE SAME DSM IP ASSETS BV (NL) 2010-03-31 EP disclosed
US-20070149667-A1 Curable compositions and rapid prototyping process using the same DSM IP ASSETS B.V. (NL) 2007-06-28 US disclosed
US-20060231982-A1 Viscosity reducible radiation curable resin composition DSM IP ASSETS B.V. (NL) 2006-10-19 US disclosed
CN-1826216-A Viscosity-reducible radiation-curable resin composition DSM IP ASSETS BV (NL) 2006-08-30 CN disclosed
EP-1646493-A2 VISCOSITY REDUCIBLE RADIATION CURABLE RESIN COMPOSITION DSM IP Assets B.V. (NL) 2006-04-19 EP disclosed
US-20060073343-A1 Curable compositions and rapid prototyping process using the same DSM IP ASSETS B.V. (NL) 2006-04-06 US disclosed
US-20050287470-A1 Curable compositions and rapid prototyping process using the same DSM IP ASSETS B.V. (NL) 2005-12-29 US disclosed
US-20050234163-A1 Curable compositions and rapid prototyping process using the same DSM IP ASSETS B.V. (NL) 2005-10-20 US disclosed
EP-1551890-A1 CURABLE COMPOSITIONS AND RAPID PROTOTYPING PROCESS USING THE SAME DSM IP Assets B.V. (NL) 2005-07-13 EP disclosed
WO-2005007759-A2 VISCOSITY REDUCIBLE RADIATION CURABLE RESIN COMPOSITION DSM IP ASSETS B.V. (NL) 2005-01-27 WO disclosed
WO-2004035643-A1 CURABLE COMPOSITIONS AND RAPID PROTOTYPING PROCESS USING THE SAME DSM IP ASSETS B.V. (NL) 2004-04-29 WO disclosed
US-20040077745-A1 Curable compositions and rapid prototyping process using the same DSM IP ASSETS B.V. (NL) 2004-04-22 US disclosed