SCHEMBL28362255

SCHEMBL28362255

CC1(C)COC(c2cc[c]cc2)OC1

nearest known ligand 0.50

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
NPC1 O15118 1/20 0.50
RAB9A P51151 1/20 0.50
MEN1 O00255 1/20 0.44
CYP2C19 P33261 1/20 0.44
KMT2A Q03164 1/20 0.44
MAPK1 P28482 1/20 0.40
SOAT1 P35610 1/20 0.36
KCNA4 P22459 1/20 0.34
KCNA1 Q09470 1/20 0.34
KCNAB1 Q14722 1/20 0.34
APAF1 O14727 1/20 0.33
POLB P06746 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18119744 0.85 SMN1; SMN2 (0.62) SMN1; SMN2NPC1RAB9AMEN1CYP2C19
SCHEMBL18119746 0.79 SMN1; SMN2 (0.57) SMN1; SMN2NPC1RAB9AMEN1CYP2C19
SCHEMBL8608558 0.79 MEN1 (0.69) SMN1; SMN2NPC1RAB9AMEN1CYP2C19
SCHEMBL11460056 0.78 SMN1; SMN2 (0.56) SMN1; SMN2NPC1RAB9AMEN1CYP2C19
SCHEMBL472727 0.76 MEN1 (0.37) MEN1CYP2C19KMT2A
SCHEMBL533185 0.76 MEN1 (0.37) MEN1CYP2C19KMT2A
SCHEMBL1179726 0.76 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AMEN1CYP2C19
SCHEMBL9946118 0.76 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AMEN1CYP2C19
SCHEMBL9636744 0.76 SMN1; SMN2 (0.54) SMN1; SMN2NPC1RAB9AMEN1CYP2C19
SCHEMBL28937620 0.76 USP1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110678532-B Organic photochromic dye and use thereof for dye sensitized solar cells 法国原子能源和替代能源委员会 2023-11-03 CN disclosed
CN-110678532-A Organic photochromic dye and application thereof in dye-sensitized solar cell 法国原子能源和替代能源委员会 2020-01-10 CN disclosed