Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | AOC1 | P19801 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30166293 | 0.82 | RIPK1 (0.55) | ALDH1A1MAOBRIPK1MAOA | |
| SCHEMBL28629177 | 0.82 | RIPK1 (0.55) | ALDH1A1MAOBRIPK1MAOA | |
| SCHEMBL28689541 | 0.81 | RIPK1 (0.51) | ALDH1A1RIPK1 | |
| SCHEMBL20161261 | 0.81 | RIPK1 (0.51) | ALDH1A1RIPK1 | |
| Hydrochloric Acid SCHEMBL28469788 | 0.80 | RIPK1 (0.50) | ALDH1A1RIPK1 | |
| SCHEMBL29136717 | 0.79 | CYP2A6 (0.35) | RIPK1 | |
| SCHEMBL30090447 | 0.79 | CYP2A6 (0.35) | RIPK1 | |
| SCHEMBL30090358 | 0.78 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL29136680 | 0.78 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL28476136 | 0.75 | RIPK1 (0.54) | ALDH1A1RIPK1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115605463-A | Inhibitors of receptor interacting protein kinase I for the treatment of diseases | 德州大学系统董事会（US） | 2023-01-13 | — | — | CN | disclosed |