Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | RIPK1 | Q13546 | 6/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30090447 | 1.00 | CYP2A6 (0.35) | CYP2A6RIPK1HCAR2 | |
| SCHEMBL30090297 | 0.82 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL28475136 | 0.82 | RIPK1 (0.38) | RIPK1 | |
| SCHEMBL28938984 | 0.79 | ALDH1A1 (0.43) | RIPK1 | |
| SCHEMBL29136680 | 0.78 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL30090358 | 0.78 | RIPK1 (0.46) | RIPK1 | |
| SCHEMBL28476136 | 0.75 | RIPK1 (0.54) | CYP2A6RIPK1 | |
| SCHEMBL28471929 | 0.73 | RIPK1 (0.36) | RIPK1 | |
| SCHEMBL18248431 | 0.72 | RIPK1 (0.67) | RIPK1 | |
| SCHEMBL22638823 | 0.72 | RIPK1 (0.51) | RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117355506-A | RIP1 modulators comprising azetidine cyclic ureas, preparation and use thereof | 维泰瑞隆有限公司 | 2024-01-05 | — | — | CN | disclosed |