SCHEMBL28939211

SCHEMBL28939211

NC(=O)C(=O)N(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.50
TSHR P16473 2/20 0.50
TDP1 Q9NUW8 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
POLB P06746 1/20 0.50
CYP3A4 P08684 1/20 0.50
PARP1 P09874 1/20 0.50
MAPT P10636 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
PMP22 Q01453 1/20 0.50
HSD17B10 Q99714 1/20 0.50
GAA P10253 1/20 0.45
ALDH1A1 P00352 3/20 0.42
CES2 O00748 2/20 0.42
CES1 P23141 2/20 0.42
DAO P14920 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
TRPM8 Q7Z2W7 1/20 0.41
ADRA2C P18825 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4125957 0.82 TDP1 (0.54) CYP2C19TSHRTDP1L3MBTL1POLB
SCHEMBL1574223 0.81 CES1 (0.55) CYP2C19TSHRTDP1L3MBTL1POLB
SCHEMBL6933107 0.78 BLM (0.50) CYP2C19TSHRTDP1L3MBTL1POLB
SCHEMBL6267389 0.78 TSHR (0.50) CYP2C19TSHRTDP1L3MBTL1POLB
SCHEMBL6280366 0.77 CES1 (0.50) CYP2C19TSHRTDP1L3MBTL1POLB
Ethylene SCHEMBL28318847 0.75 TSHR (0.46) CYP2C19TSHRTDP1L3MBTL1POLB
SCHEMBL27645357 0.75 TDP1 (0.46) CYP2C19TSHRTDP1L3MBTL1POLB
SCHEMBL11589556 0.75 TDP1 (0.46) CYP2C19TSHRTDP1L3MBTL1POLB
SCHEMBL23069336 0.75 CA2 (0.56) CYP2C19TSHRTDP1L3MBTL1POLB
Thiourea SCHEMBL15399733 0.74 MAPT (0.45) CYP2C19TSHRTDP1L3MBTL1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114441572-A Method for continuous rotation precession electron diffraction tomography 苏州青云瑞晶生物科技有限公司 2022-05-06 CN disclosed