Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 3/20 | 0.50 |
| ▸ | CES2 | O00748 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.50 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | CA4 | P22748 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PARP1 | P09874 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1574223 | 0.89 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL23069336 | 0.82 | CA2 (0.56) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL9725154 | 0.80 | CES2 (0.50) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL28515834 | 0.80 | CES1 (0.46) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL23069337 | 0.80 | ALDH1A1 (0.46) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL4125957 | 0.80 | TDP1 (0.54) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL29045863 | 0.78 | CES2 (0.48) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL10816094 | 0.78 | MAPT (0.42) | TSHRALDH1A1TDP1CYP3A4MAPT | |
| SCHEMBL11267268 | 0.78 | CES1 (0.55) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL6933107 | 0.77 | BLM (0.50) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2491980-A2 | Parakeratosis inhibitor and skin preparation for external use | SHISEIDO COMPANY LIMITED (JP) | 2012-08-29 | — | — | EP | claimed |
| EP-2491980-A2 | Parakeratosis inhibitor and skin preparation for external use | SHISEIDO COMPANY LIMITED (JP) | 2012-08-29 | — | — | EP | disclosed |
| JP-2005145925-A | SKIN CARE PREPARATION FOR EXTERNAL USE AND SKIN TORPENT | SHISEIDO CO LTD | 2005-06-09 | — | — | JP | disclosed |