Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28939434 | 0.87 | TLR7 (0.45) | HPGDTLR7ADORA2AADORA1 | |
| SCHEMBL28939428 | 0.86 | MAPK1 (0.44) | HPGDADORA2AADORA1 | |
| SCHEMBL28939432 | 0.86 | HPGD (0.47) | HPGDADORA2AADORA1 | |
| SCHEMBL28939435 | 0.81 | DAPK1 (0.45) | HPGDADORA2AADORA1 | |
| SCHEMBL28963610 | 0.76 | SCN9A (0.42) | HPGDADORA2AADORA1 | |
| SCHEMBL28963715 | 0.74 | GAA (0.42) | HPGD | |
| SCHEMBL7209567 | 0.72 | TLR7 (0.69) | TLR7 | |
| SCHEMBL5730244 | 0.71 | ADORA2A (0.51) | TLR7ADORA2AADORA1 | |
| SCHEMBL9668943 | 0.70 | AGTR1 (0.47) | — | |
| SCHEMBL9669767 | 0.70 | AGTR1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524815-B | 8-alkoxypurine derivative and preparation method and application thereof | 华南理工大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114524815-A | 8-alkoxy purine derivative and preparation method and application thereof | 华南理工大学 | 2022-05-24 | — | — | CN | disclosed |