Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28939432 | 0.86 | HPGD (0.47) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28939424 | 0.78 | HPGD (0.59) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28939435 | 0.76 | DAPK1 (0.45) | TSHRMEN1KMT2AALDH1A1LMNA | |
| SCHEMBL28939434 | 0.76 | TLR7 (0.45) | GAATSHRALDH1A1LMNAMAPT | |
| SCHEMBL28939428 | 0.75 | MAPK1 (0.44) | MEN1KMT2ALMNAHPGD | |
| SCHEMBL28939426 | 0.75 | ADORA3 (0.43) | — | |
| SCHEMBL28939430 | 0.74 | HPGD (0.41) | HPGD | |
| SCHEMBL28963610 | 0.72 | SCN9A (0.42) | HPGD | |
| SCHEMBL19291053 | 0.72 | TLR7 (0.65) | — | |
| SCHEMBL28939431 | 0.68 | ALDH1A1 (0.44) | TSHRMEN1KMT2AALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114524815-B | 8-alkoxypurine derivative and preparation method and application thereof | 华南理工大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-114524815-A | 8-alkoxy purine derivative and preparation method and application thereof | 华南理工大学 | 2022-05-24 | — | — | CN | disclosed |