Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 5/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 5/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9667639 | 0.85 | PPARG (0.52) | AGTR1AGTR2PPARG | |
| SCHEMBL9668613 | 0.81 | TLR7 (0.52) | AGTR1AGTR2 | |
| SCHEMBL9668940 | 0.80 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL9669710 | 0.80 | AGTR1 (0.53) | AGTR1AGTR2 | |
| SCHEMBL9667353 | 0.79 | AGTR1 (0.44) | AGTR1AGTR2 | |
| SCHEMBL9668943 | 0.79 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL9667282 | 0.77 | AGTR1 (0.54) | AGTR1AGTR2 | |
| SCHEMBL9667292 | 0.75 | AGTR1 (0.39) | AGTR1AGTR2 | |
| SCHEMBL10443392 | 0.74 | PPARG (0.72) | AGTR1AGTR2PPARG | |
| SCHEMBL9667346 | 0.73 | AGTR2 (0.51) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467207-A2 | Purinderivate | F. HOFFMANN-LA ROCHE AG (CH) | 1992-01-22 | — | — | EP | disclosed |