SCHEMBL289400

SCHEMBL289400

Cc1cc(=O)oc2cc(OC(=O)c3ccc(NC(=N)N)cc3)ccc12

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 12/20 0.67
ALDH1A1 P00352 10/20 0.67
GAA P10253 7/20 0.67
KMT2A Q03164 6/20 0.67
GLA P06280 5/20 0.67
MAPT P10636 5/20 0.67
NPBWR1 P48145 1/20 0.67
RAB9A P51151 3/20 0.61
MAPK1 P28482 1/20 0.56
F2 P00734 1/20 0.55
HPGD P15428 6/20 0.53
POLB P06746 2/20 0.53
NPC1 O15118 2/20 0.53
CTDSP1 Q9GZU7 1/20 0.53
HSD17B10 Q99714 3/20 0.52
CA12 O43570 1/20 0.51
CA1 P00915 1/20 0.51
CA9 Q16790 1/20 0.51
MEN1 O00255 2/20 0.51
MCL1 Q07820 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7641797 0.99 KDM4E (0.65) KDM4EALDH1A1GAAKMT2AGLA
Hydrochloric Acid SCHEMBL381749 0.98 KDM4E (0.64) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL10442289 0.82 KMT2A (0.65) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL4386227 0.82 KDM4E (0.79) KDM4EALDH1A1GAAKMT2AGLA
Hydrochloric Acid SCHEMBL31460267 0.81 KMT2A (0.63) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL29324588 0.81 TMPRSS2 (0.70) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL861206 0.81 ALDH1A1 (0.67) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL27860823 0.81 KDM4E (0.77) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL29700876 0.81 ALDH1A1 (0.69) KDM4EALDH1A1GAAKMT2AGLA
SCHEMBL662006 0.81 KDM4E (1.00) KDM4EALDH1A1GAAKMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3206723-A1 BIOLOGICAL INDICATOR American Sterilizer Company (US) 2017-08-23 EP claimed
US-9701968-B2 Biological indicator AMERICAN STERILIZER COMPANY (US) 2017-07-11 US claimed
US-20160312263-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER CO (US) 2016-10-27 US claimed
WO-2016060714-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2016-04-21 WO claimed
US-20160102335-A1 BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY 2016-04-14 US claimed
US-8507248-B2 Genetically engineered biological indicator AMERICAN STERILIZER COMPANY (US) 2013-08-13 US claimed
US-8173389-B2 Process for determining the effectiveness of a sterilization AMERICAN STERILIZER COMPANY (US) 2012-05-08 US claimed
US-20100267044-A1 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR FRANCISKOVICH PHILLIP P 2010-10-21 US claimed
EP-2084294-A2 STERILIZATION INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
EP-2084293-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR American Sterilizer Company (US) 2009-08-05 EP claimed
US-20090117603-A1 STERILIZATION INDICATOR FRANCISKOVICH PHILLIP P 2009-05-07 US claimed
WO-2008082728-A2 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-10 WO claimed
WO-2008079469-A2 GENETICALLY ENGINEERED BIOLOGICAL INDICATOR AMERICAN STERILIZER COMPANY (US) 2008-07-03 WO claimed
US-20080070231-A1 Reporter genes taken up by microorganism, and repressor gene inhibits expression AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
US-20080070272-A1 STERILIZATION INDICATOR AMERICAN STERILIZER COMPANY 2008-03-20 US claimed
EP-3897506-B1 BIOLOGICAL INDICATOR FOR LIQUID-CHEMICAL STERILIZATION SYSTEM ASP GLOBAL MFG GMBH (CH) 2026-03-04 EP disclosed
EP-3887534-B1 BIOLOGICAL STERILIZATION INDICATOR AMERICAN STERILIZER CO (US) 2026-02-25 EP disclosed
EP-0371682-A2 Rapid method for determining efficacy of a sterilization cycle and rapid read-out biological indicator MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1990-06-06 EP disclosed
EP-0352119-A2 Vampire bat salivary plasminogen activators SCHERING AKTIENGESELLSCHAFT (DE) 1990-01-24 EP disclosed
US-4423069-A Contraceptive method UNIVERSITY OF ILLINOIS FOUNDATION (US) 1983-12-27 US disclosed