Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.70 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | GBA1 | P04062 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | ACR | P10323 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL289400 | 0.81 | KDM4E (0.67) | RAB9AKMT2AALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL7641797 | 0.80 | KDM4E (0.65) | RAB9AKMT2AALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL381749 | 0.80 | KDM4E (0.64) | RAB9AKMT2AALDH1A1KDM4EMAPT | |
| Hydrochloric Acid SCHEMBL31460331 | 0.79 | CA9 (0.63) | RAB9AKMT2AMAPTGBA1POLB | |
| SCHEMBL10442289 | 0.78 | KMT2A (0.65) | KMT2AALDH1A1KDM4EMAPTGLA | |
| Hydrochloric Acid SCHEMBL31460267 | 0.78 | KMT2A (0.63) | KMT2AALDH1A1KDM4EMAPTGLA | |
| SCHEMBL10956570 | 0.74 | KMT2A (0.56) | KMT2AALDH1A1KDM4EMAPTHPGD | |
| SCHEMBL861206 | 0.73 | ALDH1A1 (0.67) | RAB9AKMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL11425856 | 0.73 | ELANE (0.53) | KMT2AKDM4EMAPTGLAMEN1 | |
| SCHEMBL7328271 | 0.72 | ACR (0.58) | RAB9AKMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226128-A1 | NOVEL COMPOUNDS WITH DUAL INHIBITION ACTIVITY AGAINST SARS-COV-2 CRITICAL ENZYMES RDRP, MPRO AND HUMAN TMPRSS2 | UNIVERSITY OF SHARJAH (AE) | 2024-07-11 | — | — | US | disclosed |
| US-20240226128-A1 | NOVEL COMPOUNDS WITH DUAL INHIBITION ACTIVITY AGAINST SARS-COV-2 CRITICAL ENZYMES RDRP, MPRO AND HUMAN TMPRSS2 | UNIVERSITY OF SHARJAH (AE) | 2024-07-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240226128-A1 | NOVEL COMPOUNDS WITH DUAL INHIBITION ACTIVITY AGAINST SARS-COV-2 CRITICAL ENZYMES RDRP, MPRO AND HUMAN TMPRSS2 | TMPRSS2, ACE2, TMPRSS4 | TMPRSS2 1/4885RAB9A 1746/4885KMT2A 1612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.