Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27712213 | 0.88 | ALDH1A1 (0.39) | POLBHSD17B10MAPTALDH1A1PKM | |
| SCHEMBL28413391 | 0.80 | CYP2C9 (0.33) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL3890644 | 0.75 | ALOX5 (0.38) | ALOX5P2RX4 | |
| SCHEMBL11843483 | 0.75 | ALDH1A1 (0.39) | POLBHSD17B10MAPTALDH1A1PKM | |
| SCHEMBL28739354 | 0.74 | CYP1A2 (0.35) | MAPTALDH1A1PKMKMT2ALMNA | |
| SCHEMBL9610546 | 0.73 | ELANE (0.39) | MAPTALDH1A1MEN1KMT2AUSP2 | |
| SCHEMBL5731715 | 0.72 | P2RX4 (0.42) | MAPTALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL18826294 | 0.72 | ELANE (0.37) | PKMALOX5P2RX4 | |
| SCHEMBL29473845 | 0.72 | CYP2C19 (0.38) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL12083433 | 0.71 | THRB (0.36) | POLBMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022063254-A1 | PHENOL DERIVATIVE AND APPLICATION THEREOF IN MEDICINE | 天地恒一制药股份有限公司 | 2022-03-31 | — | — | WO | disclosed |
| CN-114249652-A | Phenol derivative and application thereof in medicine | 天地恒一制药股份有限公司 | 2022-03-29 | — | — | CN | disclosed |