Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.43 |
| ▸ | CLK2 | P49760 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.43 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.43 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28292628 | 1.00 | KMT2A (0.52) | KMT2AGRM3SCN9AMAPTHTT | |
| SCHEMBL28292599 | 1.00 | KMT2A (0.52) | KMT2AGRM3SCN9AMAPTHTT | |
| SCHEMBL28292584 | 0.93 | SCN9A (0.46) | KMT2AGRM3SCN9AHRH3KCNH2 | |
| SCHEMBL28292616 | 0.93 | SCN9A (0.46) | KMT2AGRM3SCN9AHRH3KCNH2 | |
| SCHEMBL28294319 | 0.85 | HRH3 (0.47) | GRM3SCN9AHRH3KCNH2L3MBTL3 | |
| SCHEMBL28940980 | 0.80 | SCN9A (0.48) | KMT2AGRM3SCN9AHRH3KCNH2 | |
| SCHEMBL28294359 | 0.80 | SCN9A (0.48) | KMT2AGRM3SCN9AHRH3KCNH2 | |
| SCHEMBL29948138 | 0.79 | HRH3 (0.50) | KMT2ASCN9AHRH3KCNH2DYRK3 | |
| SCHEMBL28872982 | 0.76 | SMN1; SMN2 (0.62) | SCN9AMAPTHRH3NPC1RAB9A | |
| SCHEMBL28941103 | 0.76 | SCN9A (0.49) | KMT2ASCN9AHRH3KCNH2ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |