Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 3/20 | 0.48 |
| ▸ | GRM3 | Q14832 | 3/20 | 0.43 |
| ▸ | VNN1 | O95497 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | L3MBTL3 | Q96JM7 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28294359 | 1.00 | SCN9A (0.48) | SCN9AGRM3VNN1LIPEDRD3 | |
| SCHEMBL28292616 | 0.84 | SCN9A (0.46) | SCN9AGRM3VNN1DRD3L3MBTL1 | |
| SCHEMBL28292584 | 0.84 | SCN9A (0.46) | SCN9AGRM3VNN1DRD3L3MBTL1 | |
| SCHEMBL28941103 | 0.82 | SCN9A (0.49) | SCN9ADRD3HRH3KCNH2KMT2A | |
| SCHEMBL28941076 | 0.82 | SCN9A (0.49) | SCN9ADRD3HRH3KCNH2KMT2A | |
| SCHEMBL28294319 | 0.82 | HRH3 (0.47) | SCN9AGRM3LIPEDRD3L3MBTL1 | |
| SCHEMBL28292599 | 0.80 | KMT2A (0.52) | SCN9AGRM3VNN1L3MBTL1L3MBTL3 | |
| SCHEMBL28292628 | 0.80 | KMT2A (0.52) | SCN9AGRM3VNN1L3MBTL1L3MBTL3 | |
| SCHEMBL28940974 | 0.80 | KMT2A (0.52) | SCN9AGRM3VNN1L3MBTL1L3MBTL3 | |
| SCHEMBL21379649 | 0.75 | VNN1 (0.45) | SCN9AVNN1L3MBTL1L3MBTL3NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | claimed |
| CN-109689647-B | Bicyclic heteroaryl substituted compounds | 百时美施贵宝公司 | 2023-01-20 | — | — | CN | disclosed |